Patent · US Active

Means and methods for treating herpesvirus infection

US12414989B2 · kind B2 · utility

0Cited by

3References

19Claims

0Family size

Assignee

Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) · DE

Inventors

Wolfgang Hammerschmidt · Munich, DE
Reinhard Zeidler · Birkenfeld, DE
Dagmar Pich · Munich, DE

Key dates

Filing date	Mar 10, 2023
Grant date	Sep 16, 2025
Priority date	—
Expiry date	Mar 10, 2043

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2710/16652
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention provides herpesviruses, such as EBV, which lack at least one viral miRNA. Such herpesviruses lacking at least one viral miRNA are advantageously not capable of packaging their genome into the capsid, thereby producing HVLPs, which are substantially free of their herpesvirus genome or the nucleic acid molecule encoding the proteinaceous part of the HVLP and viral miRNA. Such HVLPs may be used as vaccine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.