Patent · US Active

Small molecule inhibitors selective for polo-like kinase protein

US12415822B2 · kind B2 · utility

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13Claims
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Key dates

Filing dateFeb 7, 2023
Grant dateSep 16, 2025
Priority date
Expiry dateFeb 15, 2044

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P35/04
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Disclosed are small molecule PLK inhibitors that can target the polo box domain (PBD). Inhibitors can have an atomic mass of about 1000 Da or less and a general structure ofFor instance, the inhibitors can include an alkyl benzamido benzoic acid core structure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.