Synthetic miniature Crispr-Cas (CasMINI) system for eukaryotic genome engineering
US12415994B2 · kind B2 · utility
0Cited by
10References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 24, 2023 |
| Grant date | Sep 16, 2025 |
| Priority date | — |
| Expiry date | Feb 24, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2310/20
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Provided herein are Cas proteins and guide RNA molecules engineered to exhibit increased activity in eukaryotic cells. The provided Cas proteins and RNA molecules are particularly useful for applications where modulation of eukaryotic nucleic acids with relatively small molecules is advantageous. Also provided are nucleic acids and vectors encoding the disclosed Cas proteins and guide RNA molecules, pharmaceutical compositions including the Cas proteins and guide RNA molecules, and methods for using the disclosed materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.