Analysis system for orthogonal access to and tagging of biomolecules in cellular compartments
US12416002B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jun 28, 2019 |
| Grant date | Sep 16, 2025 |
| Priority date | — |
| Expiry date | Dec 30, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/1093
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to a system and methods for enhancing access to nuclear informational molecules, such as DNA, RNA, and proteins, by analytical biomolecules, such as transposome complexes, by treating nuclei with a nuclear permeability enhancer, and to methods of using nuclear membrane, cell membrane, and external compartmentalization approaches as contiguity preserving elements.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.