Methods and compositions for the modification of plants

US12416009B2 · kind B2 · utility

Assignee

• Flagship Pioneering Innovations VI, LLC · US

Inventors

• Maria Helena Christine VAN ROOIJEN · Cambridge, US
• Hok Hei Tam · Newton, US
• Maier Steve Avendaño Amado · Cambridge, US
• Barry Andrew Martin · Boston, US
• Ignacio Martinez · Lexington, US
• Piotr S. Kowalski · Cork, IE
• Nataliya Vladimirovna NUKOLOVA · Cambridge, US
• Yajie Niu · Lexington, US

Key dates

• Filing date: Aug 24, 2019
• Grant date: Sep 16, 2025
• Expiry date: Aug 24, 2039

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/90
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

Disclosed herein are plant-modifying compositions including a plurality of plant messenger packs (PMPs) (e.g., including a plant extracellular vesicle (EV), or segment, portion, or extract thereof), wherein the PMPs include a plant-modifying agent, and wherein the plant-modifying agent comprising the heterologous RNA. The compositions herein are useful in methods for modifying plants such as to increase plant fitness, wherein the increase in plant fitness comprising an increase in development, growth, yield, resistance to abiotic stressors, or resistance to biotic stressors.