Recombinant particle protein product suitable for industrial production and preparation method therefor
US12416035B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 14, 2024 |
| Grant date | Sep 16, 2025 |
| Priority date | — |
| Expiry date | Jun 14, 2044 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P21/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to a recombinant particle protein suitable for industrial production and a preparation method therefor. The product is prepared by the following method: transfecting a host cell with a plasmid vector comprising a sequence encoding the recombinant particle protein for expression in the cell, harvesting and disrupting the bacterial cells, heating, incubating with urea and sodium chloride, and performing chromatography. The particle size of the product is uniform, and the batch-to-batch consistency in particle size is good. The product prepared by the method can reduce the cost of large-scale industrial mass production, the method is simple to operate, and the product has low impurity residue and a good safety profile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.