Parallelized sample processing and library prep
US12416043B2 · kind B2 · utility
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27Claims
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Key dates
| Filing date | May 28, 2021 |
| Grant date | Sep 16, 2025 |
| Priority date | — |
| Expiry date | Dec 29, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/70
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Described herein are methods, kits and systems for sample enrichment, multi-step library preparation, sample normalization, detection of sample biomolecules and combinations thereof. Enrichment and multi-step library preparation is described in the context of microfluidic workflows. Sample barcoding methods and kits are described for increasing sample throughput while reducing background in negative samples. Integrated microfluidic devices comprising sample processing unit cells coupled to an array of reaction sites are provided for integrated workflows.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.