Patent · US Active

Non-human animals expressing humanized CD3 complex

US12419282B2 · kind B2 · utility

0Cited by

3References

20Claims

0Family size

Assignee

REGENERON PHARMACEUTICALS, INC. · US

Inventors

Kara Olson · White Plains, US
Eric Smith · New York, US
Ka-Man Venus Lai · San Francisco, US
Andrew J. Murphy · Croton-on-Hudson, US
Gavin Thurston · Briarcliff Manor, US
Dayong Guo · Beijing, CN

Key dates

Filing date	Feb 15, 2024
Grant date	Sep 23, 2025
Priority date	—
Expiry date	Feb 15, 2044

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY02A50/30
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

Non-human animals, expressing humanized CD3 proteins are provided. Non-human animals, e.g., rodents, genetically modified to comprise in their genome humanized CD3 proteins are also provided. Additionally, provided are methods and compositions of making such non-human animals, as well as methods of using said non-human animals.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.