Nanophotonic sensor implants with 3D hybrid periodic-amorphous photonic crystals for wide-angle monitoring of long-term in-vivo intraocular pressure field
US12419517B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 3, 2021 |
| Grant date | Sep 23, 2025 |
| Priority date | — |
| Expiry date | Jul 7, 2044 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y20/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A biosensor includes a periodic crystalline structure first layer, and an amorphous crystalline structure second layer. The first and second layers are formed from a biocompatible silicone having a Young's Modulus E between 0.4 and 2.0 MPa. The biosensor has a pressure dependent NIR resonance peak shift of less than 15 nm over a field of view of 40°, and has an optical pressure sensitivity of between 0.38 and 2.6 nm/mm Hg. The biosensor may be formed by forming a 3D crystalline structure having a periodic amorphous crystalline first layer and an amorphous crystalline second layer. Voids of the 3D crystalline structure are filled with the biocompatible silicone/polydimethylsiloxane a material. The 3D crystalline structure is removed to form an inverse structure having a first volume of an amorphous arrangement of voids and a second volume of a periodic arrangement of voids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.