Implementing a periodic deoxyhemoglobin signal
US12419531B2 · kind B2 · utility
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Key dates
| Filing date | Jul 18, 2022 |
| Grant date | Sep 23, 2025 |
| Priority date | — |
| Expiry date | Sep 15, 2042 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB64D2045/0085
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of implementing changes in deoxyhemoglobin concentration, the method comprising: targeting a sequence of partial pressures of oxygen in arterial blood (PaCh) values in a subject using a sequential gas delivery device in a periodic input pattern; measuring a blood-oxygen level dependent (BOLD) signal in a voxel of the subject's brain using a magnetic resonance imaging device while targeting the sequence of values; comparing the pattern to the signal; and determining a vascular tissue characteristic (vessel type, vessel orientation, or pathological condition) for the voxel based on the comparison.
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