Treatment of hearing loss by inhibition of casein kinase 1
US12419876B2 · kind B2 · utility
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26References
14Claims
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Key dates
| Filing date | Oct 8, 2021 |
| Grant date | Sep 23, 2025 |
| Priority date | — |
| Expiry date | Mar 20, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2800/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods for treating hearing loss that include administering an inhibitor, e.g., a small molecule inhibitor, of casein kinase 1, preferably in combination with a treatment that stimulates Atoh1 gene expression, e.g., a gamma-secretase inhibitor, an Atoh1 stimulatory compound, or a GSK-3-beta inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.