Tuning adhesion at contacting device interfaces: geometric tools for minimizing surface fouling

US12419998B2 · kind B2 · utility

Assignees

• University of Pittsburgh—Of the Commonwealth System of Higher Education · US
• UNIVERSIDAD DE SANTIAGO DE CHILE · CL
• UPMC · US

Inventors

• William R. Wagner · Escondido, US
• Sachin Shankar Velankar · Pittsburgh, US
• Sang-Ho Ye · Springdale Township, US
• Edith Tzeng · Pittsburgh, US
• Luka Pocivavsek · Pittsburgh, US
• Enrique Cerda · Santiago, CL

Key dates

• Filing date: Oct 18, 2017
• Grant date: Sep 23, 2025
• Expiry date: Mar 21, 2040

Classification

• Technology area (CPC B): Performing Operations; Transporting
• CPC primary: B81C2201/0163
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

The present invention relates to substrates and composites having dynamic, reversible micron-level luminal surface deformation including texture or geometric instabilities, e.g., surface wrinkling and folding. The surface deformation and its reversal to the original surface form or to another, different surface form, is effective to reduce or prevent surface fouling and, more particularly, in certain applications, to reduce or prevent unwanted platelet adhesion and thrombus formation. The substrates and composites include a wide variety of designs and, more particularly, biomedical-related designs, such as, synthetic vascular graft or patch designs.