Substituted pyrazine-carboxamide derivatives

US12421218B2 · kind B2 · utility

Assignee

• Boehringer Ingelheim International GmbH · DE

Inventors

• Roland Pfau · Biberach, DE
• Georg Dahmann · Biberach an der Riß, DE
• Johann Faustus DU HOFFMANN · Biberach an der Riß, DE
• Kai Gerlach · Biberach, DE
• Riccardo GIOVANINNI · Biberach an der Riß, DE
• Christoph HOHN · Freiburg (Elbe), DE
• Stefan Just · Biberach an der Riß, DE
• Thorsten LEHMANN · Biberach, DE
• Anton Pekcec · Munich, DE
• Stefan Peters · Biberach an der Riß, DE
• Julia SCHLICHTIGER · Biberach, DE
• Heiko SOMMER · Warthausen, DE
• Christian SPECKER · Hochdorf, DE
• Dieter Wiedenmayer · Biberach an der Riß, DE

Key dates

• Filing date: Aug 14, 2024
• Grant date: Sep 23, 2025
• Expiry date: Aug 14, 2044

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D403/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to compounds of formula I a process for their manufacture, pharmaceutical compositions containing them and their use in therapy, particularly in the treatment and/or prevention of conditions having an association with the function of metabotropic glutamate receptor subtype 4 (mGluR4). A, R1, R2, R3, R4, R5 and R6 have meanings given in the description.