Patent · US Active

Pharmaceutically acceptable acid salt of free base of GLP1 receptor agonist, and preparation method therefor

US12421245B2 · kind B2 · utility

0Cited by
18References
23Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 2, 2021
Grant dateSep 23, 2025
Priority date
Expiry dateAug 18, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07B2200/13
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides pharmaceutically acceptable acid salts of (S)-2-(3S,8S)-3-(4-(3,4-dichlorobenzyloxy)phenyl-7-((S)-1-phenylpropyl)-2,3,6,7,8,9-hexahydro-[1,4]-dioxino[2,3-g]isoquinolin-8-ylformylamino)-3-(4-(2,3-dimethylpyridin-4-yl)phenyl) propionic acid (“OAD2”) and the preparation method thereof. The pharmaceutically acceptable acid salts of OAD2 provided herein may be useful in the treatment of various conditions and metabolic disorders including, but not limited to, type 2 diabetes.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.