Patent · US Active

Tetrahydropyridopyrimidine pan-KRas inhibitors

US12421253B2 · kind B2 · utility

0Cited by
6References
29Claims
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Assignee

Inventors

Key dates

Filing dateApr 24, 2024
Grant dateSep 23, 2025
Priority date
Expiry dateApr 24, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D471/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to compounds that inhibit at least one of KRas wild type, KRas G12A, KRas G12C, KRas G12D, KRas G12R, KRas G12S, KRas G12V, KRas G13D and KRas Q61H, pharmaceutical compositions comprising the compounds and methods of use therefor.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.