Lung-targeting single-domain antibodies and purification methods
US12421306B1 · kind B1 · utility
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Key dates
| Filing date | Sep 27, 2022 |
| Grant date | Sep 23, 2025 |
| Priority date | — |
| Expiry date | Apr 19, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/569
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein are single-domain antibodies (sdABs) configured for targeting to human or mammalian lung tissue. Constructs and methods of using such sdABs are also described herein, such as methods of binding with and transporting other sdABs or other cargo with beneficial functionalities, binding to and transporting biochemical or pharmaceutical species with beneficial functionalities, and a method of treating, diagnosing, or prophylactically treating a disease, condition, or malignancy. A purification method for in vivo treatment or testing is also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.