Patent · US Active

Argonaute proteins from prokaryotes and applications thereof

US12421527B2 · kind B2 · utility

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Key dates

Filing dateJan 14, 2022
Grant dateSep 23, 2025
Priority date
Expiry dateJul 14, 2044

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2800/80
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Argonaute proteins from prokaryotes (pAgos) and applications thereof are provided, the pAgo is from a mesophilic prokaryote of Kurthia massiliensis and named as KmAgo, the pAgos and applications thereof are capable of site-specific modification of intracellular and extracellular genetic material, and thus can be effectively applied to many fields of biotechnology, such as nucleic acid detection, gene editing and gene modification, and provide a new tool for gene editing, modification and molecular detection of the pAgo polypeptides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.