Means and methods for single molecule peptide sequencing
US12422438B2 · kind B2 · utility
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64References
19Claims
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Key dates
| Filing date | May 14, 2024 |
| Grant date | Sep 23, 2025 |
| Priority date | — |
| Expiry date | May 14, 2044 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/6824
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention relates to the field of biochemistry, more particularly to proteomics, more particularly to protein sequencing, even more particularly to single molecule peptide sequencing. The invention discloses methods for single molecule protein sequencing and/or amino acid identification using cleavage inducing agents which are not specific for one particular amino acid, cleave polypeptides step by step from the N-terminus onwards and provide information on the identity of the cleaved amino acids based on the reaction kinetics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.