Patent · US Active

Apparatus and method for detecting a spatial elongation of at least one adherent biological cell

US12422657B2 · kind B2 · utility

0Cited by

7References

17Claims

0Family size

Assignee

Universität Ulm · DE

Inventors

Tobias Neckernuss · Eislingen/Fils, DE
Daniel Geiger · West Chicago, US
Othmar Marti · Ulm, DE

Key dates

Filing date	Aug 20, 2019
Grant date	Sep 23, 2025
Priority date	—
Expiry date	Nov 21, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG01N2015/1495
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

An apparatus for detecting a spatial elongation of at least one adherent biological cell is provided. The apparatus contains at least one biological cell, which is adhered to a substrate, a laser for irradiating the at least one biological cell for a spatial elongation of the cell in a direction parallel to the irradiation direction and a detector for detecting the spatial elongation of the cell in the direction parallel to the radiation direction. Further, a corresponding method for spatial elongation of an adherent biological cell is provided and the uses of the apparatus and of the method proposed. Using the apparatus and method, it is possible to ascertain, from parts of adherent cells to entire groups of adherent cells, the mechanical properties in the natural, adherent state of the cell(s) in spatially selective, temporally selective and contactless fashion.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.