Patent · US Active

Microscope for imaging samples within wells of multi-well plates hold by stage and beam homogenizer for homogenizing beam

US12422660B2 · kind B2 · utility

0Cited by
10References
35Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 28, 2021
Grant dateSep 23, 2025
Priority date
Expiry dateJul 24, 2044

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG06V20/69
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The inventions provide microscopes for imaging samples within wells of multi-well plates. Microscopes of the disclosure include a beam homogenizer system that shapes a beam from a light source into a shape specific to the bottom of a well of a multi-well plate. In particular, microscopes of the disclosure can illuminate wells for imaging by passing light through a prism that is beneath the sample. The light enters the prism from the side and as refracted into the well at a steep angle such that the light only illuminates about a bottom ten microns of the well. The beam homogenizer shapes the light from the light source so that, instead of hitting the prism as a spot with an irregular shape, the light enters the prism in a substantially rectangular pattern with homogeneous optical power level over the pattern.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.