Cryoprotective compositions and methods for protection of a surgical site during cryosurgery
US12426594B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Sep 23, 2021 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Feb 16, 2044 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61B2505/05
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cryoprotective composition configured to be applied during cryotreatment of a patient includes at least one biodegradable and/or bioerodible fluid agent and at least one non-toxic cryoprotectant agent. A therapeutically effective amount of the cryoprotective composition deposited in a body space of the patient in proximity to the cryotreatment remains within at least a portion of the body space for a duration of the cryotreatment. At least a portion of a body tissue proximate to the body space is viable after the cryotreatment. A method of protecting a surgical site during prostate cryosurgery is also provided. The method includes injecting a therapeutically effective amount of the cryoprotective composition into the body space, wherein the body space is a periprostatic space of a patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.