Phenylalanine-based LAT1 inhibitors and uses thereof
US12427124B1 · kind B1 · utility
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28Claims
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Key dates
| Filing date | Feb 25, 2025 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Feb 25, 2045 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2602/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phenylalanine-based inhibitors of the Large Amino Acid Transporter 1 (LAT1) are disclosed. The compounds are useful in modulating the transcellular transport of substrates of LAT1 such as large neutral amino acids. The compounds are useful in immunomodulation therapies.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.