Compositions and methods for inhibiting ribosome inactivating proteins

US12427135B2 · kind B2 · utility

Assignee

• Rutgers, the State University of New Jersey · US

Inventors

• Nilgun E. Tumer · Montgomery, US
• Xiao-Ping Li · Nanhu, CN
• Jacques Y. Roberge · Princeton, US
• David J. Augeri · Princeton, US
• Bin Cao · Changsha, CN

Key dates

• Filing date: Mar 9, 2022
• Grant date: Sep 30, 2025
• Expiry date: Mar 9, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F5/025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The disclosure provides in one aspect a method of treating, ameliorating, and/or preventing toxicity caused by a ribosome inactivating protein (RIP) in a subject. In certain embodiments, the method comprises administering to the subject a therapeutically effective amount of at least one compound of the disclosure.