C-terminal SRC kinase inhibitors

US12427146B2 · kind B2 · utility

Assignee

• INVENTISBIO CO., LTD. · CN

Inventors

• Xing Dai · Cranford, US
• Yaolin Wang · Short Hills, US
• Yueheng Jiang · Shanghai, CN
• Yanqin LIU · Shanghai, CN
• Zhe SHI · Shanghai, CN
• Zhenwu Wang · Shanghai, CN
• Zixing HAN · Shanghai, CN
• Liangshan TAO · Shanghai, CN

Key dates

• Filing date: Dec 17, 2019
• Grant date: Sep 30, 2025
• Expiry date: Aug 26, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided herein are novel C-terminal Srk Kinase (CSK) inhibitors, e.g., having Formula G, I, II, or III. Also provided are methods of preparing the novel CSK inhibitors and method of using the novel CSK inhibitors for treating diseases or disorder such as cancer or for promoting immune response in a subject in need thereof.