Methods of neoantigen identification
US12427195B1 · kind B1 · utility
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10Claims
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Key dates
| Filing date | Mar 11, 2020 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Oct 5, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6886
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Systems and methods for identifying neoantigen peptide candidates are described. Such systems and methods can be used to generate engineered immune cells that target neoantigen peptides. In certain embodiments, the systems and methods do not require in silico epitope binding prediction algorithms. In certain embodiments, neoantigens are identified for a cancer or tumor with a low mutational burden.
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