Patent · US Active

Macromolecular prodrugs for light-emitting diodes and uses thereof

US12427196B2 · kind B2 · utility

0Cited by
1References
16Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 15, 2021
Grant dateSep 30, 2025
Priority date
Expiry dateSep 11, 2041

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/445
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are compositions comprising macromolecular photocleavable prodrug compounds of Formula (I), and pharmaceutically acceptable salts, co-crystals, tautomers, stereoisomers, solvates, hydrates, polymorphs, and isotopically enriched derivatives thereof. Also provided are methods, uses, pharmaceutical compositions, and kits involving the inventive compounds or compositions for treating and/or preventing a disease and/or condition (e.g., inflammatory disease, infectious disease, pain) in a subject, optionally comprising illumination of the compound, composition, or pharmaceutical composition with light of an absorption wavelength sufficient to cleave the bonds between each instance of L and each instance of X upon illumination with the light (e.g., light between approximately 200 nm to 500 nm).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.