Hemostatic microparticles and dressing
US12427224B1 · kind B1 · utility
Assignee
Inventors
Key dates
| Filing date | Oct 17, 2016 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Aug 30, 2038 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L2300/60
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
A method of manufacturing hemostatic particles involves heating and mixing a chitosan solution and a gelatin solution to form a chitosan/gelatin solution, adding the chitosan/gelatin mixture to oil containing an emulsifier/surfactant to form a combination of chitosan/gelatin and oil, heating and mixing the combination and then cooling and stirring the combination to form gelatin-chitosan microspheres (GCM), adding an aqueous solution of glutaraldehyde to the combination and stirring to cross-link the GCM, washing the GCM with emulsifier/surfactant to remove the oil, washing the GCM with a solvent to further remove excess oil, washing the GCM with alcohol to remove excess water, and drying the GCM.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.