2,4-disubstituted pyrimidine derivative, preparation method therefor and use thereof
US12428394B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Jun 28, 2020 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Jan 30, 2043 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention belongs to the field of chemical medicines, and particularly relates to a 2,4-disubstituted pyrimidine derivative, a preparation method therefor and a use thereof. The present invention provides a 2,4-disubstituted pyrimidine derivative, the structural formula of which is as shown in formula I. The present invention also provides a preparation method for the 2,4-disubstituted pyrimidine derivative and a use thereof. The 2,4-disubstituted pyrimidine derivative provided by the present invention can be used as a kinase inhibitor with double functional targets of JAK2 and FLT3, or a kinase inhibitor with independent functional targets of JAK2 or FLT3, thus providing a new choice for preparing a multi-target inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.