ERK inhibitors and uses thereof

US12428416B2 · kind B2 · utility

Assignees

• CALIFORNIA INSTITUTE OF TECHNOLOGY · US
• 1200 Pharma LLC · US
• The Regents of the University of California · US

Inventors

• Corey REEVES · West Hollywood, US
• Brendan M. O'Boyle · Boston, US
• Justin A. Hilf · Culver City, US
• Dylan Conklin · Los Angeles, US
• Martina S. McDermott · Los Angeles, US
• Neil A. O'Brien · Los Angeles, US
• Michael J. Palazzolo · Los Angeles, US
• Dennis Slamon · Los Angeles, US
• Steven J. Wittenberger · Mundelein, US
• Oliver C. Loson · Monrovia, US
• Michael D. Bartberger · West Hollywood, US
• Brian M. Stoltz · San Marino, US

Key dates

• Filing date: Nov 15, 2019
• Grant date: Sep 30, 2025
• Expiry date: Mar 2, 2042

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N9/1205
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present disclosure provides compounds and compositions that are inhibitors of ERK1, ERK2, or both, and methods of use thereof.