Tricyclic tetrahydroisoquinoline derivative, preparation method therefor and application thereof in medicine
US12428428B2 · kind B2 · utility
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20Claims
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Key dates
| Filing date | Jan 8, 2021 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Jan 11, 2043 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to a tricyclic tetrahydroisoquinoline derivative, a preparation method therefor and an application thereof in medicine. In particular, the present disclosure relates to a tricyclic tetrahydroisoquinoline derivative represented by general formula (I), a preparation method therefor and a pharmaceutical composition comprising said derivative, a use thereof as an estrogen receptor modulator, and a use thereof in preparing a drug for treating estrogen receptor-mediated or dependent diseases or disorders. The substituents in general formula (I) are the same as those defined in the description.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.