Therapeutic peptides and methods for treating type 2 diabetes
US12428465B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 2021 |
| Grant date | Sep 30, 2025 |
| Priority date | — |
| Expiry date | Sep 12, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K40/4215
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure provides, among other things, small peptides that are capable of interacting with CD40, thereby interfering with the ability of CD40 to interact with CD154, which impacts, e.g., inflammation and atherosclerosis. The present disclosure further provides use of such peptides in the treatment of, e.g., type 2 diabetes and auto-inflammatory disease. In particular, small peptides that are capable of interacting with CD40, thereby interfering with the ability of CD40 to interact with CD154, impact inflammation and type 2 diabetes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.