Microbiological reduction of PGA.sub.2 and 15-epi PGA.sub.2
US3930952A · kind A · utility
2Cited by
1References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 4, 1975 |
| Grant date | Jan 6, 1976 |
| Priority date | — |
| Expiry date | Apr 4, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/904
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Reduction of 7(2-[(3R and 3S)-3-hydroxy-1-octenyl]-5-oxo-3-cyclopenten-1-yl)-5-heptenoic acid by microorganisms of the genera Streptomyces, Pseudomonas and Corynebacterium is disclosed. The products 7-(2-[(3R)-3-hydroxy-1-octenyl]-5-oxo-cyclopentyl)-5-heptenoic acid(11-deoxy-15-epi-PGE.sub.2), which is novel, and 7-(2-[(3S)-3-hydroxy-1-octenyl]-5-oxo-3-cyclopentyl)-5-heptenoic acid(11-deoxy-PGE.sub.2), respectively, are useful as intermediates for the synthesis of other physiologically active ingredients.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.