2-Heteroaryl-methyl)-5,9.beta.-dialkyl-6,7-benzomorphans and salts thereof

US3931194A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Herbert Merz · Ingelheim am Rhein, DE
• Adolf Langbein
• Klaus Stockhaus
• Helmut Wick

Key dates

• Filing date: Jun 5, 1973
• Grant date: Jan 6, 1976
• Expiry date: Jun 5, 1993

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##SPC1## Wherein R is hydrogen, methyl or acetyl, PA1 R.sub.1 and R.sub.2, which may be identical to or different from each other, are each alkyl of 1 to 3 carbon atoms, PA1 R.sub.3 is hydrogen or methyl, and PA1 Y is oxygen or sulfur, And non-toxic, pharmacologically acceptable acid addition salts thereof; these compounds as well as the salts are useful as analgesics and antitussives, and opiate antagonists.