Thieno[3,4-d]pyrimidines
US3931204A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 17, 1974 |
| Grant date | Jan 6, 1976 |
| Priority date | — |
| Expiry date | Jan 17, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Thieno[3,4-d]pyrimidines of the general formula: ##SPC1## Wherein R.sub.1 is hydrogen, halogen, alkyl, alkoxy, amino, alkylamino, allylamino, hydroxy-alkylamino, cycloalkylamino, phenylamino, dialkylamino, di(hydroxyalkyl)-amino, alkyl-hydroxyalkyl-amino, pyrrolidino, piperidino, alkylpyrrolidino, alkylpiperidino, morpholino, alkyl-2-morpholino, alkyl-3-morpholino, dialkyl-3,5-morpholino, N-methylpiperazino, all said alkyl having 1 to 7 carbon atoms, said alkoxy having 1 to 5 carbon atoms and said cycloalkyl having 3 to 6 carbon atoms, R.sub.2 has the same meanings as R.sub.1 except alkyl and with the proviso that R.sub.2 is other than hydrogen or halogen, when R.sub.1 represents hydrogen or halogen and R.sub.3 is hydrogen or alkyl having 1 to 7 carbon atoms, as well as the addition salts thereof with pharmaceutically acceptable acids are, in particular, active on the cardiovascular system. Processes for their preparation are given.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.