Benzofuranyloxy and benzthienyloxy and certain 2,3-dihydro benzofuranyloxy and benzothienyloxy amidoximes
US3931240A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 6, 1974 |
| Grant date | Jan 6, 1976 |
| Priority date | — |
| Expiry date | Dec 6, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/54
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Amidoxime derivatives corresponding to the general formula: ##EQU1## and pharmaceutically acceptable acid addition salts thereof, wherein R.sub.1 and R.sub.2, which are the same or different, represent hydrogen or a straight- chain lower alkyl radical containing from 1 to 3 carbon atoms, n is 0, 1 or 2 and R is selected from the groups consisting of: Wherein X represents oxygen or sulphur, Y. . .Z represents HC-CH or C=C, R.sub.3 and R.sub.4, which are the same or different, represent hydrogen or a branched- or straight-chain lower alkyl radical containing from 1 to 3 carbon atoms with the provisos that: A. when n is 1, R.sub.1 and R.sub.2 are each hydrogen and R is selected from the groups A, B, C and D. b. when n is 2, R.sub.1 and R.sub.2 are each hydrogen and R is selected from the groups A, B, C and the group D when it represents .beta.-naphthyl. They are effective as antidepressive and antiaggressive agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.