Method of preparation of a composition having a base of 99.sup.m technetium for diagnosis by scintigraphy
US3931396A · kind A · utility
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7Claims
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Key dates
| Filing date | Mar 26, 1974 |
| Grant date | Jan 6, 1976 |
| Priority date | — |
| Expiry date | Mar 26, 1994 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S206/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing a pyrophosphate-tin composition labelled with 99.sup.m technetium for medical diagnosis by scintigraphy, especially bone scintigraphy. A pyrophosphate solution and a freshly prepared stannous chloride solution are mixed together and then neutralized to a pH within the range of 5 to 7, the mixture is eventually lyophilized in order to obtain a pyrophosphate-tin complex in powder form which is then mixed with a solution containing 99.sup.m Tc, the last-mentioned final step of the method being carried out at the moment of use. The complex has a pyrophosphate-tin molecular ratio of at least 30.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.