Patent · US Expired

N-tetrazolyl quinaldamides

US3932416A · kind A · utility

10Cited by
1References
35Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 21, 1973
Grant dateJan 13, 1976
Priority date
Expiry dateJun 21, 1993

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D215/48
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the general formula (I): ##SPC1## in which R.sub.1, R.sub.2 and R.sub.3 may be the same or different and each represents a hdyrogen atom, an alkyl group, a nitro group, a halogen atom or a group of the formula --NR.sub.4 R.sub.5 or --OR.sub.4 ; in which the groups R.sub.4 and R.sub.5 may be the same or different and each represent a hydrogen atom, or an alkyl, alkenyl or cycloalkyl group (which alkyl group may optionally be substituted by alkoxy, hydroxy, amino, alkylamino, dialkylamino or aryl groups) or R.sub.4 and R.sub.5 together with the nitrogen atom form a heterocyclic ring which may optionally contain additional hetero atoms, e.g. morpholino or piperazinyl; and R.sub.6 represents a hydrogen atom or an alkyl group. These compounds have biological activity, particularly in inhibiting the release of spasmogenic substances arising as a consequence of antigen-antibody reactions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.