Patent · US Expired

2-[(Substituted-piperidinyl or tetrahydropyridinyl)alkyl]-1H-benz[de]isoquinoline-1,3(2H)-diones

US3935227A · kind A · utility

13Cited by
3References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 28, 1974
Grant dateJan 27, 1976
Priority date
Expiry dateAug 28, 1994

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the following formula and their acid addition salts ##SPC1## Wherein R.sup.1 and R.sup.2 are independently selected from hydrogen, halogen, lower alkyl, lower alkoxy, lower alkylthio, nitro, cyano, amino and trifluoromethyl; A is a straight or branched chain alkylene of 1 to 8 carbons; and Z is selected from ##SPC2## Wherein R.sup.3 is selected from phenyl, phenyl-lower alkyl, and substituted phenyl and phenyl-lower alkyl are disclosed. These compounds exhibit antidepressant and anti-anxiety activity. In addition these compounds are useful as anti-inflammatory agents.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.