Pharmaceutical compositions containing a saccharase inhibitor

US3937817A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Werner Frommer
• Walter Puls · Wuppertal, DE
• Delf Schmidt · Wuppertal, DE

Key dates

• Filing date: Jun 20, 1974
• Grant date: Feb 10, 1976
• Expiry date: Jun 20, 1994

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/827
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention relates to a saccharase inhibitor derived from Actinoplanaceae Strain CBS 961.70, including mutants and variants thereof, means for the production of said saccharase inhibitors comprising cultivation of Actinoplanaceae Strain CBS 961.70, including mutants and variants thereof, in appropriate nutrient solutions which are characterized by being starch free under conditions most favorable to growth and production of said saccharase inhibitor and recovering a saccharase inhibitor from culture broths of said nutrient solutions, as well as the use of said inhibitor in pharmaceutically acceptable therapeutic compositions suitable for use in the treatment and relief of conditions indicative of adiposity, diabetes, pre-diabetes, hyperlipaemia (atherosclerosis), caries and the like.