Penicillin derivatives

US3939150A · kind A · utility

Assignee

• Yamanouchi Pharmaceutical Co., Ltd. · JP

Inventors

• Masuo Murakami
• Ichiro Isaka
• Khozi Nakano
• Isao Souzu · Saitama, JP
• Akio Koda · Tokyo, JP
• Teruaki Ozasa · Saitama, JP
• Teruya Kashiwagi
• Yukiyasu Murakami · Saitama, JP

Key dates

• Filing date: Oct 15, 1974
• Grant date: Feb 17, 1976
• Expiry date: Oct 15, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D499/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The penicillin derivatives represented by the formula ##SPC1## Wherein ring A represents a 5- or 6-membered single or fused ring which may contain one or more nitrogen atoms, an oxygen atom, or a sulfur atom; R.sup.1, R.sup.2, and R.sup.3, which may be the same or different, each represents a hydrogen atom, a hydroxy group, a lower alkyl group, a nitro group, a halogen atom, or an oxo group; and B represents a p-hydroxyphenyl group or a 1,4-cyclohexadien -1-yl group, and their nontoxic pharmaceutically acceptable salts. The compounds are antibiotics having excellent antibacterial activity in particular with respect to the Pseudomonas genus.