Patent · US Expired

Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production

US3940406A · kind A · utility

6Cited by
4References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 21, 1973
Grant dateFeb 24, 1976
Priority date
Expiry dateMay 21, 1993

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D213/50
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention relates to pharmacologically valuable new derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production. The new derivatives of 1-phenoxy-3-amino-propane-2-ol are suitable for the treatment and prophylaxis of diseases of the heart. Some possess pronounced .beta.-adrenalytic or anti-arythmic properties. These new derivatives have the structural formula ##SPC1## Wherein X signifies ##SPC2## And the phenyl nucleus I may be mono-, di- or trisubstituted by alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, alkoxy, alkenyloxy, phenyl, halogen or the radical --NR.sub.1 R.sub.2, in which R.sub.1 stands for alkyl or acyl and R.sub.2 for hydrogen or alkyl, together with their aldehyde condensation products and their acid addition salts.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.