Preparation of 3-alkylthiomethyl cephalosporins
US3941781A · kind A · utility
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14Claims
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Assignee
Inventor
Key dates
| Filing date | Oct 23, 1973 |
| Grant date | Mar 2, 1976 |
| Priority date | — |
| Expiry date | Oct 23, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D501/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention is addressed to a new and improved method for the preparation of 3-alkylthiomethyl-7-acylamido cephalosporins in which a 3-alkanoyloxymethyl-7-acylamido cephalosporin is reacted with an alkane thiol in aqueous medium in the presence of certain inorganic salts to produce the desired 3-alkylthiomethyl product in significantly improved yields.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.