Novel pregnane-21-oic acid derivatives
US3944577A · kind A · utility
7Cited by
3References
53Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 19, 1974 |
| Grant date | Mar 16, 1976 |
| Priority date | — |
| Expiry date | Dec 19, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J7/0095
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pregnane-21-oic acids of the formula ##SPC1## Wherein X is a hydrogen atom, a fluorine atom, or methyl; Y is a hydrogen atom, a fluorine atom, or a chlorine atom; Z is methylene, carbonyl, .beta.-hydroxymethylene, .beta.-acyloxymethylene or when Y is a chlorine atom, .beta.-fluoromethylene or .beta.-chloromethylene; V is methylene, ethylidene or vinylidene; R.sub.1 is a hydrogen atom or acyl, and physiologically acceptable salts thereof with bases and physiologically acceptable 21-esters thereof, possess topical anti-inflammatory activity with substantially no systemic activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.