Patent · US Expired

Folliculotropin releasing hormone

US3944659A · kind A · utility

2Cited by

0References

4Claims

0Family size

Inventors

Karl Folkers · Austin, US
Karl N. G. Johansson · Fagersta, SE
Bruce L. Currie · Austin, US

Key dates

Filing date	Dec 13, 1972
Grant date	Mar 16, 1976
Priority date	—
Expiry date	Dec 13, 1992

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S436/817
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for producing the Folliculotropin Releasing Hormone (FRH) biosynthetically is provided by utilizing, as key starting materials, fresh hypothalamic tissue, a buffered incubation medium, an ATP synthesizing system, radioactively labeled amino acids and a mixture of 21 naturally occuring amino acids. Biosynthesis of the FRH is accomplished by incubation of the hypothalamic tissue for a short period of time in the presence of all the reagents necessary to promote the biosynthetic system to produce the Folliculotropin Releasing Hormone (FRH) of the hypothalamus gland of mammals. Examples of methods to isolate the FRH free of the luteotropin releasing hormone (LRH) are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.