Patent · US Expired

1,3-BIS(Beta-ethylhexyl)-5-amino-5-methylhexahydropyrimidine-pyridine- 3-carboxylate, process for its preparation and pharmaceutical compositions containing this compound

US3946013A · kind A · utility

4Cited by

2References

1Claims

0Family size

Assignee

Johann A. Wulfing · DE

Inventors

Manfred Tauscher · Gronau, DE
Joachim Goring · Gronau, DE
Wolfgang Busch · Oberhaching, DE
Oskar Rohte

Key dates

Filing date	Feb 28, 1974
Grant date	Mar 23, 1976
Priority date	—
Expiry date	Feb 28, 1994

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D239/04
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

1,3-BIS(.beta.-ETHYLHEXYL)-5-AMINO-5-METHYLHEXAHYDROPYRIMIDINE PYRIDINE-3-CARBOXYLATE(HEXETIDINE NICOTINATE), WHICH HAS GREATER BACTERIOSTATIC ACTIVITY AND LOWER TOXICITY IN COMPARISON WITH HEXETIDINE OR OTHER SALTS OF HEXETIDINE, IS PREPARED BY REACTING HEXETIDINE OR AN ACID ADDITION SALT THEREOF WITH NICOTINIC ACID IN AN ORGANIC SOLVENT.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.