Polysaccharide matrices for use as adsorbents in affinity chromatography techniques
US3947352A · kind A · utility
70Cited by
1References
19Claims
0Family size
Inventors
Key dates
| Filing date | May 31, 1974 |
| Grant date | Mar 30, 1976 |
| Priority date | — |
| Expiry date | May 31, 1994 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/814
- WIPO fieldMacromolecular chemistry, polymers
- WIPO sectorChemistry
Abstract
Polysaccharide matrices, e.g., agarose, for use in certain affinity chromatography procedures, are activated with sodium metaperiodate, derivatized with a symmetrical dihydrazide and thence reductively stabilized, preferably with sodium cyanoborohydride. Moreover, intermediate Schiff bases formed from the NaIO.sub.4 -oxidized polysaccharide are selectively, reductively stabilized with said sodium cyanoborohydride.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.