Patent · US Expired

Process for augmenting connective mammalian tissue with in situ polymerizable native collagen solution

US3949073A · kind A · utility

282Cited by

1References

21Claims

0Family size

Assignee

Board of Trustees of the Leland Stanford Junior University · US

Inventors

John R. Daniels · Santa Monica, US
Terry R. Knapp · Neuchâtel, CH

Key dates

Filing date	Nov 18, 1974
Grant date	Apr 6, 1976
Priority date	—
Expiry date	Nov 18, 1994

Classification

Technology area (CPC Y)Emerging Cross-Sectional Technologies
CPC primaryY10S623/92
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A method for augmenting hard or soft connective tissue, such as skin, tendon, cartilage, bone or interstitium, in a living mammal comprising implanting a proteolytic enzyme-solubilized, purified, native, in situ polymerizable collagen solution into the mammal at the augmentation site. The solution polymerizes at the site into a stable, non-reactive fibrous mass of tissue which is rapidly colonized by host cells and vascularized.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.