Process for the preparation of cis-vincamine
US3950345A · kind A · utility
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8Claims
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Key dates
| Filing date | Feb 21, 1975 |
| Grant date | Apr 13, 1976 |
| Priority date | — |
| Expiry date | Feb 21, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D461/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is provided for the preparation of cis-vincamine by oxidising trans-vincamine with tertiary butyl hypochlorite to obtain dehydrovincamine chloride, reducing the dehydrovincamine chloride with a metal in an aqeous acidic medium and neutralising the product, and separating cis-vincamine from the resulting mixture of cis- and trans-vincamines. Cis-vincamine is useful for the treatment of circulatory disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.