Araliphatic ketones and carbinols

US3950427A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Wolfhard Engel
• Josef Nickl
• Helmut Teufel
• Gunther Engelhardt
• Ernst Seeger · Biberach, DE
• Gunter Trummlitz · Warthausen, DE

Key dates

• Filing date: Dec 12, 1974
• Grant date: Apr 13, 1976
• Expiry date: Dec 12, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C2601/14
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##SPC1## Wherein PA1 R.sub.1 is isobutyl, phenyl, o-fluoro-phenyl, o-chloro-phenyl, cyclopentyl, cyclohexyl, methyl-cyclo-hexyl or cycloheptyl, PA1 R.sub.2 is hydrogen, fluorine, chlorine or bromine, PA1 R.sub.3 is methyl, ethyl or, when R.sub.1 is phenyl, fluoro-phenyl or chloro-phenyl, or R.sub.1 is cyclohexyl and R.sub.2 is halogen, also hydrogen, PA1 Z.sub.1 and Z.sub.2 are hydrogen or together form an additional carbon-to-carbon bond, PA1 A is ##EQU1## or ##EQU2## and M IS 2, 4, 6, 8 OR WHEN R.sub.1 is halo-phenyl, isobutyl, cyclohexyl, methyl-cyclohexyl, cyclopentyl or cycloheptyl and/or R.sub.2 is halogen and/or R.sub.3 is methyl or ethyl and/or A is --CH(OH)--, also O; the compounds are useful as antiphlogistics.