Method of filling, sampling and sealing an aseptic tank with sterile product without destroying asepsis of either the sterile product or the tank and its associated valves and fittings
US3951184A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1974 |
| Grant date | Apr 20, 1976 |
| Priority date | — |
| Expiry date | Aug 12, 1994 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB65B39/004
- WIPO fieldHandling
- WIPO sectorMechanical engineering
Abstract
The method of this invention includes aseptically sealing an empty sterilized tank while maintaining asepsis of the tank, and thereafter connecting a product line to an opening in the tank, sterilizing the product line while so connected, and filling the tank with sterile product from the product line, all without destroying the aseptic condition of the tank. In addition, the method includes sampling the product in the product line during the tank filling operation while maintaining asepsis of both the product line and the tank. Finally, the method includes sealing the tank when full of sterile product, removing samples of sterile product from the tank subsequent to its filling and resealing the tank after each such sampling operation. Asepsis is maintained during each of the tank sealing, tank sampling and tank re-sampling operations.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.